Effectiveness of Infection Management Control Among Children with Febrile Neutropenia

Khoirunnisa Khoirunnisa(1*), Allenidekania Allenidekania(2), Happy Hayati(3), Aep Maulid Mulyana(4), Kurniawan Kurniawan(5)
(1) Department of Pediatric Nursing, Faculty of Nursing, Universitas Padjadjaran
(2) Department of Pediatric Nursing, Faculty of Nursing, Universitas Indonesia
(3) Department of Pediatric Nursing, Faculty of Nursing, Universitas Indonesia
(4) Nursing Internship Program, Faculty of Nursing, Universitas Padjadjaran
(5) Department of Mental Health Nursing, Faculty of Nursing, Universitas Padjadjaran
(*) Corresponding Author
DOI : 10.30604/jika.v8i3.2185


Febrile neutropenia mostly happens among children with cancer and can be prevented by infection management control. This study aimed to measure the parents’ knowledge and behavior about infection management control implementation in children with febrile neutropenia. This study used a pre-experimental design with a pre-post without control group approach. The study sample consisted of 30 parents of children with cancer who were treated with febrile neutropenia. Pre-test measured parents’ knowledge about infection control using Parents’ Knowledge Instrument before the education session begins. Infection management control consisted of parents’ education and behavior monitoring of infection control for five days in hospital. After that, the respondents did a post-test to see the effectiveness of the intervention. The infection management control was effective to reduce infection. This can be seen from the significant increase in parents’ knowledge (p=0,001) and it was in line with the change of parents’ infection management control behavior.  Parents’ infection management control in children with febrile neutropenia is effective in reducing the incidence of infection and the length of stay for children in the hospital, as well as improving the quality of life for children. Further research can be carried out with more effective methods so that infection management control can run optimally.


children with cancer, febrile neutropenia, infection control, management


Aguado, J. M., Cruz, J. J., Virizuela, J. A., Aguilar, M., Carmona, A., Cassinello, J., Gudiol, C., Jiménez Fonseca, P., Lizasoain, M., Marco, F., Ruiz, I., Ruiz, M., Salavert, M., Vicente, D., & Carratalà, J. (2017). Management of infection and febrile neutropenia in patients with solid cancer. Enfermedades Infecciosas y Microbiologia Clinica (English Ed.), 35(7), 451–460. https://doi.org/10.1016/j.eimce.2015.06.001

Anderson, K. J., Paedonc, C., Bradford, N. K., & Clark, J. E. (2018). Through Their Eyes : Parental Perceptions on Hospital Admissions for Febrile Neutropenia in Children With Cancer. https://doi.org/10.1177/1043454218777719

Dharma, K. K. (2015). Metodologi Penelitian Keperawatan: Panduan Melaksanakan dan Menerapkan Hasil Penelitian. CV Trans Info Media.

Hawley, E. L., Loney, M., & Wiece, M. (2011). Development of tools and processes to improve treatment times in patients with febrile neutropenia. Clinical Journal of Oncology Nursing, 15(5), 53–57. https://doi.org/10.1188/11.CJON.E53-E57

Hendrawati, S., Nurhidayah, I., Mediani, H. S., Mardhiyah, A., & Maryam, N. N. A. (2019). Mucositis Effect on Quality of Life of Hospitalized Children with Cancer Who Received Chemotherapy. Jurnal Keperawatan Padjadjaran, 7(1), 29–37. https://doi.org/10.24198/jkp.v7i1.1036

Khoirunnisa, K., Allenidekania, A., & Hayati, H. (2020). Effectiveness of a conservation energy model for febrile neutropenia in children with cancer. Pediatric Reports, 12, 27–29. https://doi.org/10.4081/pr.2020.8697

Loeffen, E. A. H., te Poele, E. M., Tissing, W. J. E., Boezen, H. M., & de Bont, E. S. J. M. (2016). Very early discharge versus early discharge versus non-early discharge in children with cancer and febrile neutropenia. Cochrane Database of Systematic Reviews, 2016(2). https://doi.org/10.1002/14651858.CD008382.pub2

Maree, J. E., Parker, S., Kaplan, L., & Oosthuizen, J. (2016). The Information Needs of South African Parents of Children With Cancer. https://doi.org/10.1177/1043454214563757

Mediani, H. S., Tiara, A., & Mardhiyah, A. (2019). Factors Related To The Needs Of Parents Having School Age Thalassemic Children. Jurnal Keperawatan Padjadjaran, 7(2), 173–187. https://doi.org/10.24198/jkp.v7i2.1119

Nursyirwan, S. R., & Windiastuti, E. (2017). Kejadian Demam Neutropenia pada Anak dengan Keganasan. 19(4).

Pizzo, P. A., Poplack, D. G., Adamson, P. C., Blaney, S. M., & Helman, L. J. (2015). Principles and Practice of Pediatric Oncology (7th ed). Faculty Bookshelf.2.

Rasmy, A., Amal, A., Fotih, S., & Selwi, W. (2016). Febrile Neutropenia in Cancer Patient : Epidemiology , Microbiology , Pathophysiology and Management. 5(3). https://doi.org/10.15406/jcpcr.2016.05.00165

?ahin, Z. A., & Ergüney, S. (2016). Effect on Symptom Management Education Receiving Patients of Chemotherapy. Journal of Cancer Education, 31(1), 101–107. https://doi.org/10.1007/s13187-015-0801-8

Sickbert-Bennett, E. E., Dibiase, L. M., Schade Willis, T. M., Wolak, E. S., Weber, D. J., & Rutala, W. A. (2016). Reduction of healthcare-associated infections by exceeding high compliance with hand hygiene practices. Emerging Infectious Diseases, 22(9), 1628–1630. https://doi.org/10.3201/eid2209.151440

Vedi, A., Pennington, V., O’Meara, M., Stark, K., Senner, A., Hunstead, P., Adnum, K., Londall, W., Maurice, L., Wakefield, C., & Cohn, R. J. (2015). Management of fever and neutropenia in children with cancer. Supportive Care in Cancer, 23(7), 2079–2087. https://doi.org/10.1007/s00520-014-2572-x

Wang, X. J., Chan, A., & Chan, A. (2017). Optimizing Symptoms and Management of Febrile Neutropenia among Cancer Patients : Current Status and Future Directions. https://doi.org/10.1007/s11912-017-0578-5

Article Statistic

Abstract view : 104 times
PDF (Bahasa Indonesia) views : 23 times

Dimensions Metrics

How To Cite This :


  • There are currently no refbacks.

Copyright (c) 2023 Khoirunnisa Khoirunnisa, Allenidekania Allenidekania, Happy Hayati, Aep Maulid Mulyana, Kurniawan Kurniawan

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.