Infeksi Sars-Cov-2 Pada Kehamilan dan Persalinan: Studi Literatur

Elsa Fitri Ana(1*), Ade Tyas Mayasari(2), Komalasari Komalasari(3), Hikmah Ifayanti(4), Diani Arif Wahyudi(5), Wisnu Probo Wijayanto(6)
(1) Fakultas Kesehatan, Universitas Aisyah Pringsewu
(2) Fakultas Kesehatan, Universitas Aisyah Pringsewu
(3) Fakultas Kesehatan, Universitas Aisyah Pringsewu
(4) Fakultas Kesehatan, Universitas Aisyah Pringsewu
(5) Fakultas Kesehatan, Universitas Aisyah Pringsewu
(6) Fakultas Kesehatan, Universitas Aisyah Pringsewu
(*) Corresponding Author
DOI : 10.30604/jika.v6iS1.785

Abstract

This study aims to analyze the clinical symptoms and complications of SARS-Cov-2 infection in pregnancy and childbirth. This study is a literature study that analyzes the results of a study containing clinical symptoms and complications of SARS-Cov-2 infection in pregnancy and childbirth in Asian patients. Articles were taken from several databases deemed relevant published in 2020.46 pregnant women with SARS-Cov-2 infection obtained from 5 case studies had the most complications, namely premature rupture of membrane (PROM) (10.87%), fetal distress (8.7%), preterm labor (19.57%), and preeclampsia (6.5%). The gestational age of all mothers at the time of infection was the third trimester (100%). 87% of mothers gave birth by way of a cesarean section. The most clinical symptom was fever (54.35%). Management of the prevention of transmission of SARS-Cov-2 infection in pregnant women is a matter that must be prioritized, this is done to avoid complications and transmission during childbirth and breastfeeding. Selection of the right method of delivery also needs to be considered in preventing mother-to-baby transmission during delivery.




Penelitian ini bertujuan untuk menganalisis gejala klinik dan komplikasi infeksi SARS-Cov-2 pada kehamilan dan persalinan. Penelitian ini merupakan studi literatur yang menganalisis hasil penelitian yang berisi gejala klinik dan komplikasi infeksi SARS-Cov-2 pada kehamilan dan persalinan pada pasien di Asia. Artikel diambil dari beberapa database yang dianggap relevan yang dipublikasikan tahun 2020. 46 wanita hamil dengan infeksi SARS-Cov-2 yang diperoleh dari 5 studi kasus memiliki komplikasi paling banyak yaitu premature rupture of membrane (PROM) (10,87%), fetal distress (8,7%), partus preterm (19,57%), dan prekelampsia (6,5%). Usia kehamilan seluruh ibu pada saat terinfeksi adalah trimester III (100%). 87% ibu melahirkan dengan cara section cesaria. Gejala klinik yang paling banyak adalah demam (54,35%). Manajemen pencegahan penularan infeksi SARS-Cov-2 pada ibu hamil merupakan hal yang harus diprioritaskan, hal ini dilakukan untuk menghindari komplikasi dan transmisi saat bersalin dan menyusui. Pemilihan metode persalinan yang tepat juga perlu dipertimbangkan dalam pencegahan transmisi ibu ke bayi saat bersalin.

Keywords


SARS-Cov-2 infection; Complications; Clinical symptoms; Pregnancy; Childbirth; Infeksi SARS-Cov-2; Komplikasi; Gejala klinik; Kehamilan; Persalinan

References


Cao, D., Yin, H., Chen, J., Tang, F., Peng, M., Li, R., et al. (2020). Clinical analysis of ten pregnant women with COVID-19 in Wuhan, China: A retrospective study. International Journal of Infectious Diseases. https://doi.org/10.1016/j.ijid.2020.04.047

Capobianco, G., Saderi, L., Aliberti, S., Mondoni, M., Piana, A., Dessole, F., et al. (2020). COVID-19 in pregnant women: A systematic review and meta-analysis. European Journal of Obstetrics and Gynecology and Reproductive Biology. https://doi.org/10.1016/j.ejogrb.2020.07.006

Chen, H., Guo, J., Wang, C., Luo, F., Yu, X., Zhang, W.,et al. (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The Lancet, 395(10226), 809–815. https://doi.org/10.1016/S0140-6736(20)30360-3

Di Mascio, D., Khalil, A., Saccone, G., Rizzo, G., Buca, D., Liberati, M., et al. (2020). Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis. American Journal of Obstetrics & Gynecology MFM. https://doi.org/10.1016/j.ajogmf.2020.100107

Jamieson, D. J., Honein, M. A., Rasmussen, S. A., Williams, J. L., Swerdlow, D. L., Biggerstaff, M. S., et al. (2009). H1N1 2009 influenza virus infection during pregnancy in the USA. The Lancet. https://doi.org/10.1016/S0140-6736(09)61304-0

la Gatta, A. N., Rizzo, R., Pilu, G., & Simonazzi, G. (2020). COVID19 during pregnancy: a systematic review of reported cases. American Journal of Obstetrics and Gynecology.

Li, Y., Zhao, R., Zheng, S., Chen, X., Wang, J., Sheng, X., et al. (2020). Lack of vertical transmission of severe acute respiratory syndrome Coronavirus 2, China. Emerging Infectious Diseases. https://doi.org/10.3201/eid2606.200287

Lipsitch, M., Swerdlow, D. L., & Finelli, L. (2020). Defining the Epidemiology of Covid-19 — Studies Needed. New England Journal of Medicine. https://doi.org/10.1056/nejmp2002125

Mathad, J. S., & Gupta, A. (2017). Pulmonary Infections in Pregnancy. Seminars in Respiratory and Critical Care Medicine. https://doi.org/10.1055/s-0037-1602375

Qiu, L., Liu, X., Xiao, M., Xie, J., Cao, W., Liu, Z., et al. (2020). SARS-CoV-2 is not detectable in the vaginal fluid of women with severe COVID-19 infection. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa375

Schwartz, D. A., & Graham, A. L. (2020). Potential maternal and infant outcomes from coronavirus 2019-NCOV (SARS-CoV-2) infecting pregnant women: Lessons from SARS, MERS, and other human coronavirus infections. Viruses. https://doi.org/10.3390/v12020194

Wu, Z., & McGoogan, J. M. (2020). Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China. JAMA. https://doi.org/10.1001/jama.2020.2648

Yan, J., Guo, J., Fan, C., Juan, J., Yu, X., Li, J., et al. (2020). Coronavirus disease 2019 in pregnant women: a report based on 116 cases. American Journal of Obstetrics and Gynecology, 223(1), 111.e1-111.e14. https://doi.org/10.1016/j.ajog.2020.04.014

yang, H., Sun, G., Tang, F., Peng, M., Gao, Y., Peng, J., et al. (2020). Clinical features and outcomes of pregnant women suspected of coronavirus disease 2019. Journal of Infection. https://doi.org/10.1016/j.jinf.2020.04.003

Yang, P., Wang, X., Liu, P., Wei, C., He, B., Zheng, J., & Zhao, D. (2020). Clinical characteristics and risk assessment of newborns born to mothers with COVID-19. Journal of Clinical Virology, 127. https://doi.org/10.1016/j.jcv.2020.104356

Yu, N., Li, W., Kang, Q., Xiong, Z., Wang, S., Lin, X., et al. (2020). Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. The Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(20)30176-6

Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., et al. (2020). A Novel Coronavirus from Patients with Pneumonia in China, 2019. New England Journal of Medicine. https://doi.org/10.1056/nejmoa2001017


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